For the replacement of current HIV-1 medicines in adults who meet certain requirements. See Full Indication.

Hello, Undetectable you.

Meet JULUCA.

JULUCA is a once-daily, complete HIV-1
regimen that may keep you undetectable* with
just 2 medicines in 1 small pill.

JULUCA Patient, Undetectable since 2010

*Undetectable for at least 6 months. Undetectable means keeping the amount of HIV-1 in your blood at very low levels (less than 50 copies per mL).

Now that you’re
undetectable,* have you thought about what’s next?

There are many HIV treatment options available. Do you know how many medicines are in your HIV regimen?

JULUCA Treatment Journey: Stay Undetectable

Ask your doctor if JULUCA could be a next step for you.

Taking JULUCA.

Understanding the "how" and "when" of taking JULUCA is important. Be sure to keep these considerations in mind:

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Take JULUCA every day with a meal — exactly as your doctor tells you.

Taking JULUCA with a meal is important to help get the right amount of medicine in your body. A protein drink alone does not replace a meal.

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Take JULUCA around the same time every day (or night).

Choose whatever time works best with your daily routine.

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Take JULUCA as a replacement for your current HIV regimen.

JULUCA is a complete HIV-1 regimen, so it isn’t an addition to your current treatment, and it shouldn’t be taken with any other HIV-1 medicines.

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Take JULUCA exactly as prescribed.

Do not miss a dose, change your dose, or stop taking JULUCA without talking to your doctor. Stay under a healthcare provider’s care when taking JULUCA.

Some prescription and over-the-counter medicines interact with JULUCA and need to be taken at a different time from when you take JULUCA. See the Risks & Side Effects page for more information.

Remember, it’s important to keep your overall health in mind when considering HIV treatment options. Your doctor is a good source of information. Be sure to talk with him or her if you have questions.

 

Clinical trials.

JULUCA Clinical Trial Results

This study included 2 groups of patients, those who took JULUCA for 100 weeks and those who switched from their current stable regimen§ to JULUCA at week 52. 

Patients who entered these studies were undetectable and on their current regimen for at least 6 months. They could not participate if they had liver problems, active hepatitis B, were likely to need treatment for hepatitis C during the trials, had failed a prior HIV treatment, or if they had suspected resistance to the components of JULUCA (dolutegravir or rilpivirine).

43 years

was the median age of participants.

28%

of participants were at least 50 years of age.

22%

of participants were female.

The results are in.

Icon of Undetectable Patient

In these studies, most people who were already undetectable for at least 6 months stayed undetectable when they switched to JULUCA. ||

 

AT 48 WEEKS

95% of People Who Switched to JULUCA Stayed Undetectable

1 pill with 2 medicines was as effective at keeping people undetectable|| as their previous 3- or 4-drug regimens.§

95% of people who switched to JULUCA stayed undetectable

95% of people who stayed on their current HIV regimen stayed undetectable

AT 100 WEEKS

89% of people who took JULUCA for 100 weeks stayed undetectable

93% of people who switched to JULUCA from week 52 to week 100 stayed undetectable

Both patients and their healthcare providers knew which medicines patients were taking.

Undetectable means the amount of HIV-1 in the patients' blood was at very low levels (less than 50 copies per mL).

§Regimens contained 2 nucleoside reverse transcriptase inhibitors (NRTIs) plus either an integrase strand transfer inhibitor (INSTI), a non-nucleoside reverse transcriptase inhibitor (NNRTI), or a protease inhibitor (PI).

IIYour results may vary.

What can you expect?

You may experience some side effects when switching medications. 
Here’s what people who participated in the clinical trials reportedII:

SWITCHED TO JULUCA AT THE START OF THE TRIALS

  Taking JULUCA
Common Side Effects
Weeks 1-48
Weeks 1-100
Diarrhea
2% 1%
Headache
2% 2%
Nausea
1% 2%

CONTINUED CURRENT HIV REGIMEN AT THE START OF THE TRIALS

  Taking Current HIV Regimen
Switched to JULUCA
Common Side Effects
Weeks 1-48 Weeks 52-100
Diarrhea
<1% 1%
Headache 0% 2%
Nausea 0% 1%
 

SWITCHED TO JULUCA AT THE START OF THE TRIALS

  Taking JULUCA
Discontinuation
Weeks 1-48
Weeks 1-100
People who left the study due to side effects
4% 7%

CONTINUED CURRENT HIV REGIMEN AT THE START OF THE TRIALS

  Taking Current HIV Regimen
Switched to JULUCA
Discontinuation
Weeks 1-48
Weeks 52-100
People who left the study due to side effects
<1% 3%

Of the people who left the study due to side effects, the most common side effects leading to discontinuation were psychiatric disorders:

  • 2% of patients who took JULUCA during weeks 1-48
  • 2% of patients who took JULUCA during weeks 1-100
  • <1% of patients who continued their HIV regimens during weeks 1-48
  • 1% of patients who switched to JULUCA during weeks 52-100

Your results may vary.

I went through a lot to get to undetectable, 

and reaching it was
one of the
greatest
achievements of my life.

Alex Undetectable since 2011

Watch other inspiring stories

JULUCA Patient: Alex