JULUCA is a prescription medicine that is used without other antiretroviral medicines to treat Human Immunodeficiency Virus-1 (HIV-1) infection in adults to replace their current anti-HIV-1 medicines when their healthcare provider determines that they meet certain requirements. HIV-1 is the virus that causes Acquired Immune Deficiency Syndrome (AIDS). It is not known if JULUCA is safe and effective in children.

Hello,
Undetectable you.
Meet JULUCA.

JULUCA is the only once-daily, complete HIV-1 regimen that may keep you undetectable* with 2 medicines in just 1 small pill.

*Undetectable for at least six months. Undetectable means keeping the amount of HIV-1 in your blood at very low levels (less than 50 copies per mL).

Tiera
Undetectable
since 2010

Tiera

Hello, Undetectable you.
Meet JULUCA.

Juluca is the only once-daily, complete HIV-1
regimen that may keep you undetectable* with
2 medicines in just 1 small pill.

*Undetectable for at least six months. Undetectable means keeping the amount of HIV-1 in your blood at very low levels (less than 50 copies per mL).

Tiera
Undetectable
since 2010

Tiera

What's in other single-pill regimens?

While your current regimen may be a single pill, it could contain up to 4 medicines.

2 medicines. 1 pill.

dolutegravir

rilpivirine

JULUCA is the only once-daily,
complete HIV-1 regimen that combines

2 medicines in just 1 small pill.

Now that you’re undetectable,*
have you thought about what’s next?

There are many HIV treatment options available. Do you know how many medicines are in your HIV regimen?

New Claims New Claims

Ask your doctor if JULUCA could be a next step for you.

Clinical trials.

Tested in
2 Open-label clinical trials
With more than
1,000 Undetectable adults
Evaluated at
48 & 100 Weeks

This study included two groups of patients, those who took JULUCA for 100 weeks and those who switched from their current stable regimen§ to JULUCA at week 52.

Patients who entered these studies were undetectable and on their current regimen for at least six months. They could not participate if they had liver problems, active hepatitis B, were likely to need treatment for hepatitis C during the trials, had failed a prior HIV treatment, or if they had suspected resistance to the components of JULUCA (dolutegravir or rilpivirine).

43 years

was the median
age of participants.

28%

of participants were at least 50 years of age.

22%

of participants
were female.

The results are in.
undetectable

In these studies, most people who were already undetectable for at least six months stayed undetectable when they switched to JULUCA.||

AT 48 WEEKS

95%

1 pill with 2 medicines was as effective at keeping people undetectable|| as their previous 3- or 4-drug regimens.§

95% of people who switched to Juluca stayed undetectable

95% of people who stayed on their current HIV regimen stayed undetectable

AT 100 WEEKS

89% of people who took JULUCA for 100 weeks stayed undetectable

93% of people who switched to JULUCA from week 52 to week 100 stayed undetectable

Both patients and their healthcare providers knew which medicines patients were taking.

Undetectable means the amount of HIV-1 in the patients' blood was at very low levels (less than 50 copies per mL).

§Regimens contained 2 nucleoside reverse transcriptase inhibitors (NRTIs) plus either an integrase strand transfer inhibitor (INSTI), a non-nucleoside reverse transcriptase inhibitor (NNRTI), or a protease inhibitor (PI).

IIYour results may vary.

What can you expect?

You may experience some side effects when switching medications.
Here’s what people who participated in the clinical trials reportedII:

SWITCHED TO JULUCA AT THE START OF THE TRIALS

Taking
JULUCA
Common Side Effects Weeks 1-48 Weeks 1-100
Diarrhea 2% 1%
Headache 2% 2%
Nausea 1% 2%

CONTINUED CURRENT HIV REGIMEN AT THE START OF THE TRIALS

Taking Current HIV Regimen Switched to
JULUCA
Common Side Effects Weeks 1-48 Weeks 52-100
Diarrhea <1% 1%
Headache 0% 2%
Nausea 0% 1%

SWITCHED TO JULUCA AT THE START OF THE TRIALS

Taking
JULUCA
Discontinuation Weeks 1-48 Weeks 1-100
People who left the study due to side effects 4% 7%

CONTINUED CURRENT HIV REGIMEN AT THE START OF THE TRIALS

Taking Current HIV Regimen Switched to
JULUCA
Discontinuation Weeks 1-48 Weeks 52-100
People who left the study due to side effects <1% 3%

Of the people who left the study due to side effects, the most common side effects leading to discontinuation were psychiatric disorders:

  • 2% of patients who took JULUCA during weeks 1-48
  • 2% of patients who took JULUCA during weeks 1-100
  • <1% of patients who continued their HIV regimens during weeks 1-48
  • 1% of patients who switched to JULUCA during weeks 52-100

Your results may vary.

You should always talk to your
doctor about any side effect.

Taking JULUCA.


Understanding the "how" and "when" of taking JULUCA is important. Be sure to keep these considerations in mind:

  • Take JULUCA every day with a mealexactly as your doctor tells you. Taking JULUCA with a meal is important to help get the right amount of medicine in your body. A protein drink alone does not replace a meal.
  • Take JULUCA around the same time every day (or night). Choose whatever time works best with your daily routine.
  • Take JULUCA as a replacement for your current HIV regimen. JULUCA is a complete HIV-1 regimen, so it isn’t an addition to your current treatment, and it shouldn’t be taken with any other HIV-1 medicines.
  • Take JULUCA exactly as prescribed. Do not miss a dose, change your dose, or stop taking JULUCA without talking to your doctor. Stay under a healthcare provider’s care when taking JULUCA.

Alex
Undetectable
since 2011

I went through a lot to get to
undetectable,
and reaching it was
one of the
greatest achievements
of my life.

Alex's Story Watch other inspiring stories Play